Interactomic and Pharmacological Insights on Human Sirt-1

Sirt-1 is defined as a nuclear protein involved in the molecular mechanisms of inflammation and neurodegeneration through the de-acetylation of many different substrates even if experimental data in mouse suggest both its cytoplasmatic presence and nucleo-cytoplasmic shuttling upon oxidative stress....

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Bibliographic Details
Main Authors: Sharma, Ankush, Gautam, Vasu, Costantini, Susan, Paladino, Antonella, Colonna, Giovanni
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311038/
https://ncbi.nlm.nih.gov/pubmed/22470339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00040
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