Progesterone Receptor Activates Msx2 Expression by Downregulating TNAP/Akp2 and Activating the Bmp Pathway in EpH4 Mouse Mammary Epithelial Cells

Previously we demonstrated that EpH4 mouse mammary epithelial cells induced the homeobox transcription factor Msx2 either when transfected with the progesterone receptor (PR) or when treated with Bmp2/4. Msx2 upregulation was unaffected by Wnt inhibitors s-FRP or Dkk1, but was inhibited by the Bmp a...

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Bibliographic Details
Main Authors: Fleming, Jodie M., Ginsburg, Erika, Goldhar, Anita S., Plant, Joshua, Vonderhaar, Barbara K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310875/
https://ncbi.nlm.nih.gov/pubmed/22457812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034058
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