Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression studies have not identified genetic factors that...

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Autores principales: Chow, Maggie L., Pramparo, Tiziano, Winn, Mary E., Barnes, Cynthia Carter, Li, Hai-Ri, Weiss, Lauren, Fan, Jian-Bing, Murray, Sarah, April, Craig, Belinson, Haim, Fu, Xiang-Dong, Wynshaw-Boris, Anthony, Schork, Nicholas J., Courchesne, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310790/
https://ncbi.nlm.nih.gov/pubmed/22457638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002592
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