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Lesion selectivity in blockage of lambda exonuclease by DNA damage.

Various kinds of DNA damage block the 3' to 5' exonuclease action of both E. coli exonuclease III and T4 DNA polymerase. This study shows that a variety of DNA damage likewise inhibits DNA digestion by lambda exonuclease, a 5' to 3' exonuclease. The processive degradation of DNA by the enzyme is blo...

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Pubblicato in:Nucleic Acids Res
Autore principale: Mattes, W B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1990
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1695729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.13.3723
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