An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway

Vitamin D(3) is critical for the regulation of calcium and phosphate homeostasis. In some individuals, mineral homeostasis can be disrupted by long-term therapy with certain antiepileptic drugs and the antimicrobial agent rifampin, resulting in drug-induced osteomalacia, which is attributed to vitam...

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Detalhes bibliográficos
Main Authors: Wang, Zhican, Lin, Yvonne S., Zheng, Xi Emily, Senn, Tauri, Hashizume, Takanori, Scian, Michele, Dickmann, Leslie J., Nelson, Sidney D., Baillie, Thomas A., Hebert, Mary F., Blough, David, Davis, Connie L., Thummel, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310418/
https://ncbi.nlm.nih.gov/pubmed/22205755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.076356
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