An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway

Vitamin D(3) is critical for the regulation of calcium and phosphate homeostasis. In some individuals, mineral homeostasis can be disrupted by long-term therapy with certain antiepileptic drugs and the antimicrobial agent rifampin, resulting in drug-induced osteomalacia, which is attributed to vitam...

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Главные авторы: Wang, Zhican, Lin, Yvonne S., Zheng, Xi Emily, Senn, Tauri, Hashizume, Takanori, Scian, Michele, Dickmann, Leslie J., Nelson, Sidney D., Baillie, Thomas A., Hebert, Mary F., Blough, David, Davis, Connie L., Thummel, Kenneth E.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310418/
https://ncbi.nlm.nih.gov/pubmed/22205755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.076356
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