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Fibrin Specific Peptides Derived by Phage Display: Characterization of Peptides and Conjugates for Imaging

Peptides that bind to fibrin but not to fibrinogen or serum albumin were selected from phage display libraries as targeting moieties for thrombus molecular imaging probes. Three classes of cyclic peptides (cyclized via disulfide bond between two Cys) were identified with consensus sequences XArXCPY(...

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Detalhes bibliográficos
Main Authors: Kolodziej, Andrew F., Nair, Shrikumar A., Graham, Philip, McMurry, Thomas J., Ladner, Robert C., Wescott, Charles, Sexton, Daniel J., Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310290/
https://ncbi.nlm.nih.gov/pubmed/22263840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200613e
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