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GISP increases neurotransmitter receptor stability by down-regulating ESCRT-mediated lysosomal degradation

GPCR interacting scaffold protein (GISP) is a multi-domain brain-specific scaffold protein that can regulate GABA(B) receptor complexes by both enhancing their surface expression and by inhibiting their lysosomal degradation. GISP retards degradation of GABA(B) receptors through its interaction with...

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Autors principals: Kantamneni, Sriharsha, Holman, David, Wilkinson, Kevin A., Nishimune, Atsushi, Henley, Jeremy M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310152/
https://ncbi.nlm.nih.gov/pubmed/19154774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.01.011
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