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A mammalian temperature-sensitive mutation affecting G1 progression results from a single amino acid substitution in asparagine synthetase.

ts11 is a temperature-sensitive (ts) mutant isolated from the BHK-21 Syrian hamster cell line that is blocked in the G1 phase of the cell cycle at the non-permissive temperature (39.5 degrees C). We previously showed that the human gene encoding asparagine synthetase (AS) transformed ts11 cells to a...

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Bibliográfalaš dieđut
Publikašuvnnas:Nucleic Acids Res
Váldodahkkit: Gong, S S, Basilico, C
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Oxford University Press 1990
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1972978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.12.3509
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