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Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population

BACKGROUND: Hyperhomocysteinemia (>15 µmol/L) is highly prevalent in South Asian populations including Pakistan. In order to investigate the genetic determinants of this condition, we studied 6 polymorphisms in genes of 3 enzymes - methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C), methi...

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Bibliografische gegevens
Hoofdauteurs: Yakub, Mohsin, Moti, Naushad, Parveen, Siddiqa, Chaudhry, Bushra, Azam, Iqbal, Iqbal, Mohammad Perwaiz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310006/
https://ncbi.nlm.nih.gov/pubmed/22470444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033222
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