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Normalisation to Blood Activity Is Required for the Accurate Quantification of Na/I Symporter Ectopic Expression by SPECT/CT in Individual Subjects

The utilisation of the Na/I symporter (NIS) and associated radiotracers as a reporter system for imaging gene expression is now reaching the clinical setting in cancer gene therapy applications. However, a formal assessment of the methodology in terms of normalisation of the data still remains to be...

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Bibliografiske detaljer
Main Authors: Richard-Fiardo, Peggy, Franken, Philippe R., Lamit, Audrey, Marsault, Robert, Guglielmi, Julien, Cambien, Béatrice, Graslin, Fanny, Lindenthal, Sabine, Darcourt, Jacques, Pourcher, Thierry, Vassaux, Georges
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309932/
https://ncbi.nlm.nih.gov/pubmed/22470517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034086
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