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Homology-independent discovery of replicating pathogenic circular RNAs by deep sequencing and a new computational algorithm
A common challenge in pathogen discovery by deep sequencing approaches is to recognize viral or subviral pathogens in samples of diseased tissue that share no significant homology with a known pathogen. Here we report a homology-independent approach for discovering viroids, a distinct class of free...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309787/ https://ncbi.nlm.nih.gov/pubmed/22345560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117815109 |
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