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Toxicological Assessment of the Cochleate Derived from Neisseria meningitidis Proteoliposome in Sprague Dawley Rats

BACKGROUND: The AFCo1 cochleate is a potential novel adjuvant derived from Neisseria meningitidis B proteoliposome. AIM: The aim was to assessing the safety of AFCo1 by single and repeated doses in Sprague Dawley rats. MATERIALS AND METHODS: Rats were grouped for treatment with AFCo1, placebo formul...

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Detalhes bibliográficos
Main Authors: Infante-Bourzac, Juan Francisco, Sifontes-Rodríguez, Sergio, Arencibia-Arrebola, Daniel Francisco, Hernández-Salazar, Tamara, Fariñas-Medina, Mildrey, Pérez, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309621/
https://ncbi.nlm.nih.gov/pubmed/22454827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1947-2714.93888
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