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Role of the Methoxy Group in Immune Responses to mPEG-Protein Conjugates

[Image: see text] Anti-PEG antibodies have been reported to mediate the accelerated clearance of PEG-conjugated proteins and liposomes, all of which contain methoxyPEG (mPEG). The goal of this research was to assess the role of the methoxy group in the immune responses to mPEG conjugates and the pot...

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Detalhes bibliográficos
Main Authors: Sherman, Merry R., Williams, L. David, Sobczyk, Monika A., Michaels, Shawnya J., Saifer, Mark G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309606/
https://ncbi.nlm.nih.gov/pubmed/22332808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200551b
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