Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma

Childhood maltreatment, through epigenetic modification of the glucocorticoid receptor gene (NR3C1), influences the hypothalamic–pituitary–adrenal axis (HPA axis). We investigated whether childhood maltreatment and its severity were associated with increased methylation of the exon 1(F) NR3C1 promot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Perroud, N, Paoloni-Giacobino, A, Prada, P, Olié, E, Salzmann, A, Nicastro, R, Guillaume, S, Mouthon, D, Stouder, C, Dieben, K, Huguelet, P, Courtet, P, Malafosse, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309499/
https://ncbi.nlm.nih.gov/pubmed/22832351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.60
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg