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Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia
Genotype–phenotype correlations of common monogenic diseases revealed that the degree of deviation of mutant genes from wild-type structure and function often predicts disease onset and severity. In complex disorders such as schizophrenia, the overall genetic risk is still often >50% but genotype...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group
2011
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309490/ https://ncbi.nlm.nih.gov/pubmed/22833191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.43 |
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