Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia

Genotype–phenotype correlations of common monogenic diseases revealed that the degree of deviation of mutant genes from wild-type structure and function often predicts disease onset and severity. In complex disorders such as schizophrenia, the overall genetic risk is still often >50% but genotype...

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Detalhes bibliográficos
Principais autores: Papiol, S, Malzahn, D, Kästner, A, Sperling, S, Begemann, M, Stefansson, H, Bickeböller, H, Nave, K-A, Ehrenreich, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309490/
https://ncbi.nlm.nih.gov/pubmed/22833191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.43
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