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Gas1 Interferes with AβPP Trafficking by Facilitating the Accumulation of Immature AβPP in Endoplasmic Reticulum-Associated Raft Subdomains
The amyloid-β protein precursor (AβPP) is a type I transmembrane protein that undergoes maturation during trafficking in the secretory pathway. Proper maturation and trafficking of AβPP are necessary prerequisites for AβPP processing to generate amyloid-β (Aβ), the core component of Alzheimer’s dise...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309423/ https://ncbi.nlm.nih.gov/pubmed/21971401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110434 |
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