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Cardiac Cellular Coupling and the Spread of Early Instabilities in Intracellular Ca(2+)

Recent experimental and modeling studies demonstrate the fine spatial scale, complex nature, and independent contribution of Ca(2+) dynamics as a proarrhythmic factor in the heart. The mechanism of progression of cell-level Ca(2+) instabilities, known as alternans, to tissue-level arrhythmias is not...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jia, Zhiheng, Bien, Harold, Shiferaw, Yohannes, Entcheva, Emilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309286/
https://ncbi.nlm.nih.gov/pubmed/22455912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.034
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