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Removal of AMPA Receptors (AMPARs) from Synapses Is Preceded by Transient Endocytosis of Extrasynaptic AMPARs

AMPA receptors (AMPARs) are dynamically regulated at synapses, but the time course and location of their exocytosis and endocytosis are not known. Therefore, we have used ecliptic pHluorin-tagged glutamate receptor 2 to visualize changes in AMPAR surface expression in real time. We show that synapti...

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Autori principali: Ashby, Michael C., De La Rue, Sarah A., Ralph, G. Scott, Uney, James, Collingridge, Graham L., Henley, Jeremy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309030/
https://ncbi.nlm.nih.gov/pubmed/15175386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1042-04.2004
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