Production of Interferon α by Human Immunodeficiency Virus Type 1 in Human Plasmacytoid Dendritic Cells Is Dependent on Induction of Autophagy

Background. The mechanisms responsible for interferon α (IFN-α) production by plasmacytoid dendritic cells (pDCs) during human immunodeficiency virus type 1 (HIV-1) infection are unknown. This research examined the roles of Toll-like receptor 7 (TLR7) and autophagy in IFN-α production by pDCs during...

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Bibliographic Details
Main Authors: Zhou, Dejiang, Kang, Kyung Hee, Spector, Stephen A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308911/
https://ncbi.nlm.nih.gov/pubmed/22396599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis187
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