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Specialized Function of Yeast Isa1 and Isa2 Proteins in the Maturation of Mitochondrial [4Fe-4S] Proteins

Most eukaryotes contain iron-sulfur cluster (ISC) assembly proteins related to Saccharomyces cerevisiae Isa1 and Isa2. We show here that Isa1 but not Isa2 can be functionally replaced by the bacterial relatives IscA, SufA, and ErpA. The specific function of these “A-type” ISC proteins within the fra...

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Autors principals: Mühlenhoff, Ulrich, Richter, Nadine, Pines, Ophry, Pierik, Antonio J., Lill, Roland
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308834/
https://ncbi.nlm.nih.gov/pubmed/21987576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296152
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