Platelet-activating Factor Receptor Agonists Mediate Xeroderma Pigmentosum A Photosensitivity

To date, oxidized glycerophosphocholines (Ox-GPCs) with platelet-activating factor (PAF) activity produced non-enzymatically have not been definitively demonstrated to mediate any known disease processes. Here we provide evidence that these Ox-GPCs play a pivotal role in the photosensitivity associa...

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Detalhes bibliográficos
Main Authors: Yao, Yongxue, Harrison, Kathleen A., Al-Hassani, Mohammed, Murphy, Robert C., Rezania, Samin, Konger, Raymond L., Travers, Jeffrey B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308814/
https://ncbi.nlm.nih.gov/pubmed/22303003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332395
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