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Picomolar Concentrations of Free Zinc(II) Ions Regulate Receptor Protein-tyrosine Phosphatase β Activity
As key enzymes in the regulation of biological phosphorylations, protein-tyrosine phosphatases are central to the control of cellular signaling and metabolism. Zinc(II) ions are known to inhibit these enzymes, but the physiological significance of this inhibition has remained elusive. Employing meta...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
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American Society for Biochemistry and Molecular Biology
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308757/ https://ncbi.nlm.nih.gov/pubmed/22275360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.320796 |
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