Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration

Little is known about how neutrophils and other cells establish a single zone of actin assembly during migration. A widespread assumption is that the leading edge prevents formation of additional fronts by generating long-range diffusible inhibitors or by sequestering essential polarity components....

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Main Authors: Houk, Andrew R., Jilkine, Alexandra, Mejean, Cecile O., Boltyanskiy, Rostislav, Dufresne, Eric R., Angenent, Sigurd B., Altschuler, Steven J., Wu, Lani F., Weiner, Orion D.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308728/
https://ncbi.nlm.nih.gov/pubmed/22265410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.050
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