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Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme

Hectd1 mutant mouse embryos exhibit the neural tube defect exencephaly associated with abnormal cranial mesenchyme. Cellular rearrangements in cranial mesenchyme are essential during neurulation for elevation of the neural folds. Here we investigate the molecular basis of the abnormal behavior of He...

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Detalhes bibliográficos
Main Authors: Sarkar, Anjali A., Zohn, Irene E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308699/
https://ncbi.nlm.nih.gov/pubmed/22431752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201105101
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