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A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning

During mitosis in budding yeast, cortically anchored dynein generates pulling forces on astral microtubules to position the mitotic spindle across the mother–bud neck. The attachment molecule Num1 is required for dynein anchoring at the cell membrane, but how Num1 assembles into stationary cortical...

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Detalhes bibliográficos
Main Authors: Tang, Xianying, Germain, Bryan St., Lee, Wei-Lih
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308694/
https://ncbi.nlm.nih.gov/pubmed/22431751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112017
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