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Balanced Ero1 activation and inactivation establishes ER redox homeostasis
The endoplasmic reticulum (ER) provides an environment optimized for oxidative protein folding through the action of Ero1p, which generates disulfide bonds, and Pdi1p, which receives disulfide bonds from Ero1p and transfers them to substrate proteins. Feedback regulation of Ero1p through reduction a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308690/ https://ncbi.nlm.nih.gov/pubmed/22412017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110090 |
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