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Molecular basis of the mechanism of thiol oxidation by hydrogen peroxide in aqueous solution: challenging the S(N)2 paradigm
The oxidation of cellular thiol containing compounds, such as glutathione and protein Cys residues, is considered to play an important role in many biological processes. Among possible oxidants, hydrogen peroxide (H(2)O(2)) is known to be produced in many cell types as a response to a variety of ext...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308630/ https://ncbi.nlm.nih.gov/pubmed/22303921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200540z |
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