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Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?

INTRODUCTION: Studies investigating genetic risk factors for susceptibility to rheumatoid arthritis (RA) studied anti-citrullinated peptide antibody (CCP)-positive RA more frequently than anti-CCP-negative RA. One of the reasons for this is the perception that anti-CCP-negative RA may include patien...

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Bibliographic Details
Main Authors: De Rooy, Diederik PC, Willemze, Annemiek, Mertens, Bart, Huizinga, Tom WJ, Van der Helm-van Mil, Annette HM
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308115/
https://ncbi.nlm.nih.gov/pubmed/22032620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3505
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