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The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus

The focus of the present review is on the extent to which epigenetic alterations influence the development of systemic lupus erythematosus. Lupus is a systemic autoimmune disease characterized by the production of autoantibodies directed at nuclear self-antigens. A DNA methylation defect in CD4+ T c...

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Detalhes bibliográficos
Main Authors: Hughes, Travis, Sawalha, Amr H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308098/
https://ncbi.nlm.nih.gov/pubmed/22044622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3484
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