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HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients

INTRODUCTION: The revised shared epitope (SE) concept in rheumatoid arthritis (RA) is based on the presence (S) or absence (X) of the SE RAA amino acid motif at positions 72 to 74 of the third hypervariable region of the various human leucocyte antigen (HLA)-DRB1 alleles. The purpose of this study w...

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Detalhes bibliográficos
Main Authors: Meyer, Pieter WA, Hodkinson, Bridget, Ally, Mahmood, Musenge, Eustasius, Wadee, Ahmed A, Fickl, Heidi, Tikly, Mohammed, Anderson, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308093/
https://ncbi.nlm.nih.gov/pubmed/21978430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3479
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