Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

INTRODUCTION: Mast cells have been implicated to play a functional role in arthritis, especially in autoantibody-positive disease. Among the cytokines involved in rheumatoid arthritis (RA), IL-17 is an important inflammatory mediator. Recent data suggest that the synovial mast cell is a main produce...

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Bibliographic Details
Main Authors: Suurmond, Jolien, Dorjée, Annemarie L, Boon, Mariëtte R, Knol, Edward F, Huizinga, Tom WJ, Toes, René EM, Schuerwegh, Annemie JM
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308080/
https://ncbi.nlm.nih.gov/pubmed/21933391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3466
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