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Mechanisms of B cell autoimmunity in SLE

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is known to be associated with polyclonal B-cell hyperreactivity. The underlying causes of the diffuse B-cell over-reactivity are unclear, but potential candidates include (a) intrinsic hyper-reactivity leading to polyclonal B-...

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Detalhes bibliográficos
Main Authors: Dörner, Thomas, Giesecke, Claudia, Lipsky, Peter E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308063/
https://ncbi.nlm.nih.gov/pubmed/22078750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3433
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