Synergistic Interactions between Aβ, Tau, and α-Synuclein: Acceleration of Neuropathology and Cognitive Decline

Alzheimer's disease (AD), the most prevalent age-related neurodegenerative disorder, is characterized pathologically by the accumulation of β-amyloid (Aβ) plaques and tau-laden neurofibrillary tangles. Interestingly, up to 50% of AD cases exhibit a third prevalent neuropathology: the aggregatio...

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Главные авторы: Clinton, Lani K., Blurton-Jones, Mathew, Myczek, Kristoffer, Trojanowski, John Q., LaFerla, Frank M.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308018/
https://ncbi.nlm.nih.gov/pubmed/20505094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0490-10.2010
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