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The Targeted Intracellular Delivery of Cytochrome-C Protein to Tumors Using Lipid-Apolipoprotein Nanoparticles
Intracellular-acting therapeutic proteins offer a promising clinical alternative to extracellular-acting agents, but are limited in efficacy by their low permeability into the cell cytoplasm. We have developed a nanoparticle (NP) composed of lipid (DOTAP/DOPE) and apolipoprotein (APO A-I) to mediate...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307951/ https://ncbi.nlm.nih.gov/pubmed/22365810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.02.010 |
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