Identifying New Therapeutic Targets via Modulation of Protein Corona Formation by Engineered Nanoparticles

BACKGROUND: We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide insight into disease development. ME...

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Главные авторы: Arvizo, Rochelle R., Giri, Karuna, Moyano, Daniel, Miranda, Oscar R., Madden, Benjamin, McCormick, Daniel J., Bhattacharya, Resham, Rotello, Vincent M., Kocher, Jean-Pierre, Mukherjee, Priyabrata
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307759/
https://ncbi.nlm.nih.gov/pubmed/22442705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033650
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