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Identifying New Therapeutic Targets via Modulation of Protein Corona Formation by Engineered Nanoparticles
BACKGROUND: We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide insight into disease development. ME...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307759/ https://ncbi.nlm.nih.gov/pubmed/22442705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033650 |
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