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Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue

We previously reported that adenosine monophosphate-activated protein kinase (AMPK) activity is lower in adipose tissue of morbidly obese individuals who are insulin resistant than in comparably obese people who are insulin sensitive. However, the number of patients and parameters studied were small...

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Detalhes bibliográficos
Main Authors: Xu, X. Julia, Gauthier, Marie-Soleil, Hess, Donald T., Apovian, Caroline M., Cacicedo, Jose M., Gokce, Noyan, Farb, Melissa, Valentine, Rudy J., Ruderman, Neil B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307656/
https://ncbi.nlm.nih.gov/pubmed/22323564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P022905
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