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Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα
Ursodeoxycholic acid (UDCA, ursodiol) is used to prevent damage to the liver in patients with primary biliary cirrhosis. The drug also prevents the progression of colorectal cancer and the recurrence of high-grade colonic dysplasia. However, the molecular mechanism by which UDCA elicits its benefici...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307643/ https://ncbi.nlm.nih.gov/pubmed/22223860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021733 |
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