An apoA-I mimetic peptibody generates HDL-like particles and increases alpha-1 HDL subfraction in mice

The aim of this study is to investigate the capability of an apoA-I mimetic with multiple amphipathic helices to form HDL-like particles in vitro and in vivo. To generate multivalent helices and to track the peptide mimetic, we have constructed a peptibody by fusing two tandem repeats of 4F peptide...

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Autors principals: Lu, Shu-Chen, Atangan, Larissa, Won Kim, Ki, Chen, Michelle M., Komorowski, Renee, Chu, Carolyn, Han, Joon, Hu, Sylvia, Gu, Wei, Véniant, Murielle, Wang, Minghan
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307641/
https://ncbi.nlm.nih.gov/pubmed/22287724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M020438
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