Inhaled Carbon Monoxide Attenuates Myocardial Inflammatory Cytokine Expression in a Rat Model of Cardiopulmonary Bypass

Carbon monoxide (CO), a by-product of Heme metabolism, is a potent modulator of inflammation. Low dose inhaled CO has demonstrated reduced lung and kidney injury in animal models of cardiopulmonary bypass (CPB). We evaluated the impact of low dose inhaled CO on systemic, pulmonary, and myocardial in...

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Main Authors: Pulido, Juan N., Neal, James R., Mantilla, Carlos B., Agarwal, Shvetank, Lee, Won-Yeon, Scott, Phillip D., Hubmayr, Rolf D., Zhan, Wen-Zhi, Sieck, Gary C., Farrugia, Gianrico, Ereth, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of ExtraCorporeal Technology 2011
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Abstract
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307597/
https://ncbi.nlm.nih.gov/pubmed/22164452
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