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Disease mutations in disordered regions—exception to the rule?

Intrinsically disordered proteins (IDPs) have been implicated in a number of human diseases, including cancer, diabetes, neurodegenerative and cardiovascular disorders. Although for some of these conditions molecular mechanisms are now better understood, the big picture connecting distinct structura...

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Detalles Bibliográficos
Main Authors: Vacic, Vladimir, Iakoucheva, Lilia M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307532/
https://ncbi.nlm.nih.gov/pubmed/22080206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mb05251a
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