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The tertiary structure of the four-way DNA junction affords protection against DNase I cleavage.

The accessibility of phosphodiester bonds in the DNA of four-way helical junctions has been probed with the nuclease DNase I. Regions of protection were observed on all four strands of the junctions, that tended to be longer on the strands that are exchanged between the coaxially stacked pairs of he...

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Autores principales: Murchie, A I, Carter, W A, Portugal, J, Lilley, D M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC330742/
https://ncbi.nlm.nih.gov/pubmed/2339051
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