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microRNA-279 acts through the JAK/STAT pathway to regulate circadian behavioral output in Drosophila

Although molecular components of the circadian clock are known, mechanisms that transmit signals from the clock and produce rhythmic behavior are poorly understood. We found through a genetic screen that over-expression of microRNA miR-279 disrupts rest:activity rhythms in Drosophila. Deletion of mi...

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Autori principali: Luo, Wenyu, Sehgal, Amita
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307393/
https://ncbi.nlm.nih.gov/pubmed/22305007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.024
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