Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

AIMS: Remodelling and regional gradients in expression of connexins (Cx) are thought to contribute to atrial electrical dysfunction and atrial fibrillation. We assessed the effect of interaction between Cx43, Cx40, and Cx45 on atrial cell-to-cell coupling and inward Na current (I(Na)) in engineered...

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Bibliographic Details
Main Authors: Desplantez, Thomas, McCain, Megan L., Beauchamp, Philippe, Rigoli, Ghislaine, Rothen-Rutishauser, Barbara, Parker, Kevin Kit, Kleber, Andre G.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307380/
https://ncbi.nlm.nih.gov/pubmed/22287588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs025
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