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2′-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling

[Image: see text] Chemical modification can significantly enrich the structural and functional repertoire of ribonucleic acids and endow them with new outstanding properties. Here, we report the syntheses of novel 2′-azido cytidine and 2′-azido guanosine building blocks and demonstrate their efficie...

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Detalhes bibliográficos
Main Authors: Fauster, Katja, Hartl, Markus, Santner, Tobias, Aigner, Michaela, Kreutz, Christoph, Bister, Klaus, Ennifar, Eric, Micura, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307367/
https://ncbi.nlm.nih.gov/pubmed/22273279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200510k
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