Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

Metastasis and drug resistance are the major causes of mortality in patients with pancreatic cancer. Once developed, the progression of pancreatic cancer metastasis is virtually unstoppable with current therapies. Here we report the remarkable clinical outcome of a patient with advanced, gemcitabine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Villarroel, Maria C., Rajeshkumar, N.V., Garrido-Laguna, Ignacio, De Jesus-Acosta, Ana, Jones, Siân, Maitra, Anirban, Hruban, Ralph H., Eshleman, James R., Klein, Alison, Laheru, Daniel, Donehower, Ross, Hidalgo, Manuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307340/
https://ncbi.nlm.nih.gov/pubmed/21135251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0893
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