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Interplay between β1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins

The Snail family of transcription factors has been implicated in pancreatic cancer progression. We recently showed that Snail (Snai1) promotes membrane-type 1 matrix metalloproteinase (MT1-MMP)- and ERK1/2-dependent scattering of pancreatic cancer cells in three-dimensional type I collagen. In this...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shields, Mario A., Krantz, Seth B., Bentrem, David J., Dangi-Garimella, Surabhi, Munshi, Hidayatullah G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307329/
https://ncbi.nlm.nih.gov/pubmed/22232555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308940
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