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Quaternary Structure Controls Ligand Dynamics in Soluble Guanylate Cyclase
Soluble guanylate cyclase (sGC) is the mammalian endogenous nitric oxide (NO) receptor. The mechanisms of activation and deactivation of this heterodimeric enzyme are unknown. For deciphering them, functional domains can be overexpressed. We have probed the dynamics of the diatomic ligands NO and CO...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307277/ https://ncbi.nlm.nih.gov/pubmed/22223482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299297 |
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