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Quaternary Structure Controls Ligand Dynamics in Soluble Guanylate Cyclase

Soluble guanylate cyclase (sGC) is the mammalian endogenous nitric oxide (NO) receptor. The mechanisms of activation and deactivation of this heterodimeric enzyme are unknown. For deciphering them, functional domains can be overexpressed. We have probed the dynamics of the diatomic ligands NO and CO...

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Hlavní autoři: Yoo, Byung-Kuk, Lamarre, Isabelle, Martin, Jean-Louis, Negrerie, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307277/
https://ncbi.nlm.nih.gov/pubmed/22223482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299297
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