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Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that promotes angiogenesis, metabolic reprogramming, and other critical aspects of cancer biology. The four-and-a-half LIM domain (FHL) proteins are a family of LIM domain-only proteins implicated in transcriptional regulation and suppress...

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Autors principals: Hubbi, Maimon E., Gilkes, Daniele M., Baek, Jin H., Semenza, Gregg L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307273/
https://ncbi.nlm.nih.gov/pubmed/22219185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278630
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