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Development and Use of Integral Assays in Clinical Trials

Clinical trials that include integral biomarkers to determine eligibility, assign treatment or assess outcome must employ robust assays to measure the molecular analyte of interest. The decision to develop a biomarker assay into a test suitable for use in humans should be driven by clinical need, i....

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Bibliographic Details
Main Authors: Schilsky, Richard L., Doroshow, James H., LeBlanc, Michael, Conley, Barbara A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307146/
https://ncbi.nlm.nih.gov/pubmed/22422406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2202
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